Meiotic segregation of complex reciprocal translocations: direct analysis of the spermatozoa of a t(5;13;14) carrier.

doi:10.1016/j.fertnstert.2011.01.159

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Article

Meiotic segregation of complex reciprocal translocations: direct analysis of the spermatozoa of a t(5;13;14) carrier.

Fertility and sterility - 1 Jun 2011

Pellestor Franck, Puechberty Jacques, Weise Anja, Lefort Geneviève, Anahory Tal, Liehr Thomas, Sarda Pierre

Abstract excerpt

OBJECTIVE: To directly study the meiotic segregation of a complex reciprocal translocation (CCR) as well as the occurrence of an interchromosomal effect. DESIGN: In situ sperm fluorescence in situ hybridization (FISH) analysis. SETTING: Department of Cytogenetics and INSERM research center. PATIENT(S): A male carrier of a balanced complex reciprocal translocation t(5;13;14)(q23;q21;q31). INTERVENTION(S): Sperm...

Topics

Abortion, Habitual
Adult
Chromosome Aberrations
Chromosome Segregation
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 5
Female
Genetic Predisposition to Disease
Humans
In Situ Hybridization, Fluorescence
Male

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Meiosis

Pregnancy

Sperm Count

Sperm Motility

Spermatozoa

Translocation, Genetic

Source

Open in PubMed

Identifiers

PMID: 21367411
DOI: 10.1016/j.fertnstert.2011.01.159

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