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Article

Effect of carriers' sex on meiotic segregation patterns and chromosome stability of reciprocal translocations.

Reproductive biomedicine online - 1 Dec 2021

Lin Liuyan, Chen Xueyao, Wang Jing, Li Rong, Ding Chenhui, Cai Bing, Zhou Canquan, Xu Yanwen

Abstract excerpt

RESEARCH QUESTION: Does the sex of reciprocal translocation carriers affect meiotic segregation patterns and stability of non-translocated chromosomes during meiosis? DESIGN: A total of 790 couples who underwent preimplantation genetic testing for reciprocal translocations by using the single nucleotide polymorphism (SNP) array platform between October 2016 and December 2019 were included. Among them, 294 couples...

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PMID: 34654612
DOI: 10.1016/j.rbmo.2021.08.017

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