Article
Age-dependent chloride channel expression in skeletal muscle fibres of normal and HSA(LR) myotonic mice.
The Journal of physiology - 1 Mar 2013
DiFranco Marino, Yu Carl, Quiñonez Marbella, Vergara Julio L
Abstract excerpt
Abstract We combine electrophysiological and optical techniques to investigate the role that the expression of chloride channels (ClC-1) plays on the age-dependent electrical properties of mammalian muscle fibres. To this end, we comparatively evaluate the magnitude and voltage dependence of chloride currents (ICl), as well as the resting resistance, in fibres isolated from control and human skeletal actin...
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