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Article

Quantitative descriptors for the effect of nature/mechanical properties of solid substrates on fibroblast morphology.

Journal of applied biomaterials & functional materials - 1 Jan 2012

Siani Alessandro, Robert-Nicoud Ghislaine, Cellesi Francesco, Tirelli Nicola

Abstract excerpt

PURPOSE: Cell shape is a powerful indicator of cell activity. This study aimed to validate the use of numeric descriptors for the assessment of the effect of substrate mechanical properties on the morphology of 2D cultured fibroblasts. METHODS: Two fibroblast cell types, the 3T3 murine cell line and primary Human Dermal Fibroblasts (HDF) were cultured on substrates (fibrin, silicone, Tissue Culture PolyStyrene)...

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Identifiers

PMID: 23242875
DOI: 10.5301/JABFM.2012.10355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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