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Article

CXCL12/CXCR4 Signaling is Required for the Maintenance of Mouse Spermatogonial Stem Cells

1 Jan 2012

Abstract excerpt

Continual spermatogenesis relies on the activities of a tissue-specific stem cell population referred to as spermatogonial stem cells (SSCs). Fate decisions of stem cells are influenced by their niche environments, a major component of which is soluble factors secreted by support cells. At present, the factors that constitute the SSC niche are undefined. We explored the role of chemokine (C-X-C motif) ligand 12...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 23239029
DOI: 10.1242/jcs.119826

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