Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells

6 May 2009

Abstract excerpt

Spermatogonial stem cells (SSCs) self-renew throughout life to produce progenitor cells that are able to differentiate into spermatozoa. However, the mechanisms underlying the cell fate determination between self-renewal and differentiation have not yet been delineated. Culture conditions and growth factors essential for self-renewal and proliferation of mouse SSCs have been investigated, but no information is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19419993
DOI: 10.1530/rep-08-0510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cellsPMID 19419993Read ↗

Paracrine Wnt/β-catenin signaling mediates proliferation of undifferentiated spermatogonia in the adult mouse testisSemantic proximity Read ↗

Wnt5a is a cell-extrinsic factor that supports self-renewal of mouse spermatogonial stem cellsSemantic proximity Read ↗

The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells.Semantic proximity Read ↗

Spermatogonial stem cells: A story of self-renewal and differentiationSemantic proximity Read ↗

Signaling molecules and pathways regulating the fate of spermatogonial stem cellsSemantic proximity Read ↗

Prepubertal human spermatogonia and mouse gonocytes share conserved gene expression of germline stem cell regulatory moleculesSemantic proximity Read ↗

Spermatogonial stem cells, infertility and testicular cancerSemantic proximity Read ↗

Regulation of spermatogonial stem cell self-renewal in mammals.Semantic proximity Read ↗

Spermatogonial stem cell regulation and spermatogenesisSemantic proximity Read ↗

WNT5A regulates the proliferation, apoptosis and stemness of human stem Leydig cells via the β-catenin signaling pathwaySemantic proximity Read ↗

Mammalian gonocyte and spermatogonia differentiation: recent advances and remaining challengesSemantic proximity Read ↗

Molecular regulation of spermatogonial stem cell renewal and differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.