Article
Interactions of apoptotic cells with macrophages in radiation-induced bystander signaling.
Radiation research - 1 Feb 2013
Rastogi Shubhra, Boylan Michael, Wright Eric G, Coates Philip J
Abstract excerpt
Nontargeted effects that result in ongoing cellular and tissue damage show genotype-dependency in murine models with CBA/Ca, but not C57BL/6, exhibiting sensitivity to induced genomic instability. In vivo, radiation exposure is associated with genotype-dependent macrophage activation, and these cells are a source of bystander signaling involving cytokines and reactive oxygen and nitrogen species. The mechanisms...
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