Article
Meta-analysis of RAGE gene polymorphism and coronary heart disease risk.
PloS one - 1 Jan 2012
Wang Jun, Zou Lianjiang, Song Zhigang, Lang Xilong, Huang Shengdong, Lu Fanglin, Han Lin, Xu Zhiyun
Abstract excerpt
BACKGROUND: Recent data from human and animal studies have shown an upregulated expression of advanced glycosylation end product-specific receptor (RAGE) in human atherosclerotic plaques 1 and in retina, messangial, and aortic vessels, suggesting an important role of RAGE in the pathogenesis of atherothrombotic diseases. In the past few years, the relationship between RAGE polymorphisms (-429T/C, -374T/A, and...
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