Article
Association study of polymorphisms in the receptor for advanced glycation end-products (RAGE) gene with susceptibility and prognosis of heart failure.
Gene - 15 Nov 2012
Cohen Carolina Rodrigues, Diel Vanessa Backes Nascimento, La Porta Vanessa Laubert, Rohde Luís Eduardo, Biolo Andréia, Clausell Nadine, Dos Santos Kátia Gonçalves
Abstract excerpt
BACKGROUND: Functional polymorphisms in the receptor for advanced glycation end-products (RAGE) gene have been implicated in several vascular diseases. However, to date, no study investigated the association of RAGE polymorphisms with heart failure (HF). OBJECTIVE: In this study we tested the hypothesis that the 63-bp insertion/deletion, the -374T>A (rs1800624) and the -429T>C (rs1800625) polymorphisms in the...
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