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Article

Granting specificity for breast cancer cells using a hepatitis B core particle with a HER2-targeted affibody molecule.

Journal of biochemistry - 1 Mar 2013

Nishimura Yuya, Mimura Wakiko, Mohamed Suffian Izzat Fahimuddin, Amino Tomokazu, Ishii Jun, Ogino Chiaki, Kondo Akihiko

Abstract excerpt

Capsid-like particles consisting of a hepatitis B core (HBc) protein have been studied for their potential as carriers for drug delivery systems (DDS). The hollow HBc particle, which is formed by the self-assembly of core proteins comprising 183 aa residues, has the ability to bind to various cells non-specifically via the action of an arginine-rich domain. In this study, we developed an engineered HBc particle...

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Identifiers

PMID: 23235317
DOI: 10.1093/jb/mvs140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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