Article
Immunoconjugates and new molecular targets in hairy cell leukemia.
Hematology. American Society of Hematology. Education Program - 1 Jan 2012
Kreitman Robert J
Abstract excerpt
Hairy cell leukemia (HCL) is a B-cell malignancy that in its classic form is exquisitely sensitive to single-agent purine analog therapy, but that is associated in many patients with late relapse and eventual purine analog resistance. Minimal residual disease, which is present in most patients achieving complete remission with purine analogs, retains Ags that are ideal for targeted therapy. Rituximab, which...
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