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Article

Multidrug resistance protein 2 genetic polymorphism and colorectal cancer recurrence in patients receiving adjuvant FOLFOX-4 chemotherapy.

Molecular medicine reports - 1 Feb 2013

Mirakhorli Mojgan, Rahman Sabariah Abdul, Abdullah Syahrilnizam, Vakili Masoud, Rozafzon Reza, Khoshzaban Ahad

Abstract excerpt

Multidrug resistance protein 2 (MRP2), encoded by the ATP-binding cassette C2 (ABCC2) gene, is an efflux pump located on the apical membrane of many polarized cells, which transports conjugate compounds by an ATP-dependent mechanism. The correlation of G1249A ABCC2 polymorphism with the development of colorectal cancer (CRC) and poor prognosis was evaluated in patients who were treated with...

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Identifiers

PMID: 23232902
DOI: 10.3892/mmr.2012.1226

Genes

ABCC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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