Article
Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin.
Cancer chemotherapy and pharmacology - 1 Oct 2009
Kim Jong Gwang, Chae Yee Soo, Sohn Sang Kyun, Moon Joon Ho, Ryoo Hun Mo, Bae Sung Hwa, Kum Yoonseop, Jeon Seong Woo, Lim Kyoung-Hoon, Kang Byung-Mo, Park In-Ja, Choi Gyu Seog, Jun Soo-Han
Abstract excerpt
PURPOSE: The present study analyzed the polymorphisms of apoptosis-related genes and their impact on the response to chemotherapy and survival of patients with colorectal cancer. PATIENTS AND METHODS: A total of 76 patients with recurrent or metastatic colorectal cancer treated with capecitabine and oxaliplatin (XELOX) combination chemotherapy were enrolled in the present study. The single nucleotide...
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