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Article

Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation.

PloS one - 1 Jan 2012

Boije Henrik, Harun-Or-Rashid Mohammad, Lee Yu-Jen, Imsland Freyja, Bruneau Nicolas, Vieaud Agathe, Gourichon David, Tixier-Boichard Michèle, Bed'hom Bertrand, Andersson Leif, Hallböök Finn

Abstract excerpt

The genetic basis and mechanisms behind the morphological variation observed throughout the animal kingdom is still relatively unknown. In the present work we have focused on the establishment of the chicken comb-morphology by exploring the Pea-comb mutant. The wild-type single-comb is reduced in size and distorted in the Pea-comb mutant. Pea-comb is formed by a lateral expansion of the central comb anlage into...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23227218
DOI: 10.1371/journal.pone.0050890
PMCID: PMC3515514

Genes

SHH
SOX5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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