Article
Quantitative effect of a CNV on a morphological trait in chickens.
PloS one - 1 Jan 2015
Moro Céline, Cornette Raphaël, Vieaud Agathe, Bruneau Nicolas, Gourichon David, Bed'hom Bertrand, Tixier-Boichard Michèle
Abstract excerpt
Copy Number Variation has been associated with morphological traits, developmental defects or disease susceptibility. The autosomal dominant Pea-comb mutation in chickens is due to the massive amplification of a CNV in intron 1 of SOX5 and provides a unique opportunity to assess the effect of variation in the number of repeats on quantitative traits such as comb size and comb mass in Pea-comb chickens. The...
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