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Article

Controlling antimicrobial resistance through targeted, vaccine-induced replacement of strains.

PloS one - 1 Jan 2012

Tekle Yonas I, Nielsen Kaare M, Liu Jingzhou, Pettigrew Melinda M, Meyers Lauren A, Galvani Alison P, Townsend Jeffrey P

Abstract excerpt

Vaccination has proven effective in controlling many infectious diseases. However, differential effectiveness with regard to pathogen genotype is a frequent reason for failures in vaccine development. Often, insufficient immune response is induced to prevent infection by the diversity of existing serotypes present in pathogenic populations of bacteria. These vaccines that target a too narrow spectrum of serotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23227198
DOI: 10.1371/journal.pone.0050688
PMCID: PMC3515573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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