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Article

Building pyramids against the evolutionary emergence of pathogens.

Proceedings. Biological sciences - 13 Mar 2024

Gandon Sylvain, Guillemet Martin, Gatchitch François, Nicot Antoine, Renaud Ariane C, Tremblay Denise M, Moineau Sylvain

Abstract excerpt

Mutations allowing pathogens to escape host immunity promote the spread of infectious diseases in heterogeneous host populations and can lead to major epidemics. Understanding the conditions that slow down this evolution is key for the development of durable control strategies against pathogens. Here, we use theory and experiments to compare the efficacy of three strategies for the deployment of resistance: (i) a...

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PMID: 38471546
DOI: 10.1098/rspb.2023.1529
PMCID: PMC10932699

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