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Why the evolution of vaccine resistance is less of a concern than the evolution of drug resistance

17 Dec 2018

Abstract excerpt

Vaccines and antimicrobial drugs both impose strong selection for resistance. Yet only drug resistance is a major challenge for 21st century medicine. Why is drug resistance ubiquitous and not vaccine resistance? Part of the answer is that vaccine resistance is far less likely to evolve than drug resistance. But what happens when vaccine resistance does evolve? We review six putative cases. We find that in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30559199
DOI: 10.1073/pnas.1717159115

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