Article
Risk of red queen dynamics in pneumococcal vaccine strategy.
Trends in microbiology - 1 Aug 2011
Jefferies Johanna M C, Clarke Stuart C, Webb Jeremy S, Kraaijeveld Alex R
Abstract excerpt
Pathogens increasingly evade current vaccines, and new strategies to control them are needed. There is mounting evidence that replacement of vaccine serotypes of Streptococcus pneumoniae with non-vaccine serotypes has taken place following widespread use of limited-serotype conjugate vaccines. New strategies to control vaccine evasion are needed and understanding evolutionary theory is important for the...
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