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Article

Relationship between melatonin receptor 1B and insulin receptor substrate 1 polymorphisms with gestational diabetes mellitus: a systematic review and meta-analysis.

Scientific reports - 22 Aug 2014

Zhang Yan, Sun Cheng-Ming, Hu Xiang-Qin, Zhao Yue

Abstract excerpt

Studies have investigated the relationship between genetic variants and risk of gestational diabetes mellitus (GDM). However, the results remain inconclusive. The aim of this study was to investigate the association of rs10830963 and rs1387153 variants in melatonin receptor 1B (MTNR1B) and rs1801278 variant in insulin receptor substrate 1 (IRS1) with GDM susceptibility. Electronic database of PubMed, Medline,...

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Topics

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Share to Diabetes, Gestational
Share to Genetic Association Studies
Share to Insulin Receptor Substrate Proteins
Share to Odds Ratio
Share to Polymorphism, Genetic
Share to Pregnancy
Share to Publication Bias
Share to Receptor, Melatonin, MT2

Source

Open in PubMed Open full text

Identifiers

PMID: 25146448
DOI: 10.1038/srep06113
PMCID: PMC4141258

Genes

IRS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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