Article
Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus.
BMC medical genetics - 10 Jun 2011
Kim Jason Y, Cheong Hyun Sub, Park Byung-Lae, Baik Sei Hyun, Park Sunmin, Lee Si Won, Kim Min-Hyoung, Chung Jin Hoon, Choi June Seek, Kim Moon-Young, Yang Jae-Hyug, Cho Dong-Hee, Shin Hyoung Doo, Kim Sung-Hoon
Abstract excerpt
BACKGROUNDS: Two SNPs in melatonin receptor 1B gene, rs10830963 and rs1387153 showed significant associations with fasting plasma glucose levels and the risk of Type 2 Diabetes Mellitus (T2DM) in previous studies. Since T2DM and gestational diabetes mellitus (GDM) share similar characteristics, we suspected that the two genetic polymorphisms in MTNR1B may be associated with GDM, and conducted association studies...
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