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Article

Analysis of 20 genes at chromosome band 12q13: <i>RACGAP1</i> and <i>MCRS1</i> overexpression in nonsmall‐cell lung cancer

8 Dec 2012

Abstract excerpt

Chromosomal aberrations at 12q13 are frequent in nonsmall-cell lung cancer (NSCLC). Here, we examined mRNA expression of 20 genes within chromosome band 12q13 by quantitative real-time polymerase chain reaction in NSCLC. Of the 20 genes, nine were upregulated, while two genes were downregulated. Among the nine upregulated genes, mRNA values of RACGAP1, MCRS1, EIF4B, WNT1, and PTGES3 were significantly higher in...

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PMID: 23225332
DOI: 10.1002/gcc.22030

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