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Article

Hyperreactive platelet phenotypes: relationship to altered serotonin transporter number, transport kinetics and intrinsic response to adrenergic co-stimulation.

Thrombosis and haemostasis - 1 Jan 2013

Berger Jeffrey S, Becker Richard C, Kuhn Cynthia, Helms Michael J, Ortel Thomas L, Williams Redford

Abstract excerpt

The mechanism underlying a hyperreactive platelet phenotype remains unknown. Since serotonin has been shown to influence platelet biology and atherothrombosis, we sought to investigate the association of platelet serotonin transporter number, binding affinity, and uptake kinetics with platelet aggregation. A total of 542 healthy volunteers had light transmittance platelet aggregometry measured in response to...

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Identifiers

PMID: 23223800
DOI: 10.1160/TH12-03-0202
PMCID: PMC3582386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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