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Article

Functional characterization of novel variants in the CETP promoter and the LIPC gene in subjects with hyperalphalipoproteinemia.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2013

Plengpanich Wanee, Tongkobpetch Siraprapa, Shotelersuk Vorasuk, Le Goff Wilfried, Khovidhunkit Weerapan

Abstract excerpt

BACKGROUND: Variants in the CETP and the LIPC genes, encoding cholesteryl ester transfer protein and hepatic lipase, respectively, are associated with high levels of HDL-cholesterol or hyperalphalipoproteinemia (HALP). Recently, we have identified three novel variants in the CETP promoter and two novel variants in LIPC in Thai subjects with HALP. In this study, we investigated the functions of these 5 variants in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Variation

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Share to Lipid Metabolism, Inborn Errors

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 23219720
DOI: 10.1016/j.cca.2012.11.024

Genes

CETP
LIPC

Variants

Provenance

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