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Article

Genetic variation of PLTP modulates lipoprotein profiles in hypoalphalipoproteinemia.

Journal of lipid research - 1 Apr 2006

Aouizerat Bradley E, Engler Mary B, Natanzon Yanina, Kulkarni Medha, Song James, Eng Celeste, Huuskonen Jarkko, Rivera Christopher, Poon Annie, Bensley Matt, Sehnert Amy, Zellner Christian, Malloy Mary, Kane John, Pullinger Clive R

Abstract excerpt

Phospholipid transfer protein (PLTP) participates in key processes in lipoprotein metabolism, including interparticle phospholipid transfer, remodeling of HDL, cholesterol and phospholipid efflux from peripheral tissues, and the production of hepatic VLDL. The impact of PLTP on reverse cholesterol transport suggests that the gene may harbor sequence anomalies that contribute to disorders of HDL metabolism. The...

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Source

Identifiers

PMID: 16388083
DOI: 10.1194/jlr.M500476-JLR200

Genes

PLTP

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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