Article
Novel mutations of cholesteryl ester transfer protein (CETP) gene in Japanese hyperalphalipoproteinemic subjects.
Clinica chimica acta; international journal of clinical chemistry - 22 Mar 2012
Ohtani Rumiko, Inazu Akihiro, Noji Yoshihiro, Wakasugi Takanobu, Miwa Kenji, Tada Hayato, Kawashiri Masa-aki, Noguchi Tohru, Nohara Atsushi, Kobayashi Junji, Koizumi Junji, Yamagishi Masakazu, Mabuchi Hiroshi
Abstract excerpt
BACKGROUND: The half of hyperalphalipoproteinemia (HALP) in Japan is caused by CETP gene mutations. Other than two prevalent mutations (D442G and Intron 14 splicing donor site +1G>A), some rare CETP mutations are found in Japanese HALP subjects. METHODS: CETP gene analysis of genomic DNA from subjects was performed by restriction fragment length polymorphism (RFLP) and sequencing analysis. Mutations which were...
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