Major histocompatibility complex class II polymorphisms are associated with the development of anti-resorptive agent-induced osteonecrosis of the jaw.

doi:10.1016/j.jcms.2012.10.018

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Article

Major histocompatibility complex class II polymorphisms are associated with the development of anti-resorptive agent-induced osteonecrosis of the jaw.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery - 1 Jan 2013

Stockmann Philipp, Nkenke Emeka, Englbrecht Matthias, Schlittenbauer Tilo, Wehrhan Falk, Rauh Claudia, Beckmann Matthias W, Fasching Peter A, Kreusch Thomas, Mackensen Andreas, Wullich Bernd, Schett Georg, Spriewald Bernd M

Abstract excerpt

The aetiology of anti-resorptive agent-induced osteonecrosis of the jaw (ARONJ) is still under debate. Clinical and genetic risk factors are currently being investigated to help understand its pathogenesis. This case-control study analysed a large number of cancer patients (n = 230) under therapy with intravenous bisphosphonates, half of which were diagnosed with ARONJ. Multiple myeloma, greater patient age and...

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PMID: 23218978
DOI: 10.1016/j.jcms.2012.10.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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