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Article

A Survey of Drug Resistance <i>bla</i> Genes Originating from Synthetic Plasmid Vectors in Six Chinese Rivers

6 Dec 2012

Abstract excerpt

Antibiotic resistance poses a significant challenge to human health and its rate continues to rise globally. While antibiotic-selectable synthetic plasmid vectors have proved invaluable tools of genetic engineering, this class of artificial recombinant DNA sequences with high expression of antibiotic resistance genes presents an unknown risk beyond the laboratory setting. Contamination of environmental microbes...

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PMID: 23215020
DOI: 10.1021/es302760s

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