Synergistic interplay of UV radiation and urban particulate matter induces impairment of autophagy and alters cellular fate in senescence‐prone human dermal fibroblasts

Abstract excerpt

Skin aging is a complex process influenced by intrinsic factors and environmental stressors, including ultraviolet (UV) radiation and air pollution, among others. In this study, we investigated the effects of UVA and UVB radiation, combined with urban particulate matter (UPM), on human dermal fibroblasts (HDF). We show here that treatment of HDF with a subcytotoxic dose of UVA/UVB results in a series of events...

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