Article
Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma.
Cancer letters - 28 Jun 2013
Ludewig Gabriele, Robertson Larry W
Abstract excerpt
PCBs are carcinogens, but for many decades it was assumed that PCBs may not possess initiating activity. Initiation is a process that involves changes in the DNA sequence, often, but not exclusively produced through DNA adduction by a reactive compound or reactive oxygen species (ROS). DNA adduct...
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