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Article

AT1 mutations and risk of atrial fibrillation based on genotypes from 71,000 individuals from the general population.

British journal of clinical pharmacology - 1 Jul 2013

Marott Sarah C W, Nordestgaard Børge G, Jensen Gorm B, Tybjaerg-Hansen Anne, Benn Marianne

Abstract excerpt

AIMS: Activation of the angiotensin II type 1 (AT1 ) receptor has been shown to mediate the structural and electrical remodelling of the atrial myocardium associated with atrial fibrillation. We hypothesized that AT1 genotypic variation is associated with atrial fibrillation or diseases predisposing to atrial fibrillation, such as hypertension, heart failure, ischaemic heart disease and myocardial infarction, in...

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Identifiers

PMID: 23210602
DOI: 10.1111/bcp.12050
PMCID: PMC3703234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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