Article
Renin-angiotensin system gene polymorphisms and atrial fibrillation.
Circulation - 6 Apr 2004
Tsai Chia-Ti, Lai Ling-Ping, Lin Jiunn-Lee, Chiang Fu-Tien, Hwang Juey-Jen, Ritchie Marylyn D, Moore Jason H, Hsu Kuan-Lih, Tseng Chuen-Den, Liau Chiau-Suong, Tseng Yung-Zu
Abstract excerpt
BACKGROUND: The activated local atrial renin-angiotensin system (RAS) has been reported to play an important role in the pathogenesis of atrial fibrillation (AF). We hypothesized that RAS genes might be among the susceptibility genes of nonfamilial structural AF and conducted a genetic case-control study to demonstrate this. METHODS AND RESULTS: A total of 250 patients with documented nonfamilial structural AF...
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