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Article

The flavonoid isoquercitrin promotes neurite elongation by reducing RhoA activity.

PloS one - 1 Jan 2012

Palazzolo Gemma, Horvath Peter, Zenobi-Wong Marcy

Abstract excerpt

BACKGROUND: Neurite formation and synaptic patterning are fundamental to the development of a functional nervous system. Flavonoids are natural molecules known for having beneficial effects on brain health through diverse molecular pathways. Cytoskeletal changes occurring during neuritogenesis and synapse formation often involve Rho GTPases. Here we hypothesized that the flavonoid isoquercitrin promotes neuronal...

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Identifiers

PMID: 23209630
DOI: 10.1371/journal.pone.0049979
PMCID: PMC3510166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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