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Article

New lipoxygenase inhibitors of reactive oxygen species production in cellular models of amyloid (A2) toxicities.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Pontiki Eleni, Kontogiorgis Christos, Xu Yanan, Hadjipavlou-Litina Dimitra, Luo Yuan

Abstract excerpt

Neuroinflammation and oxidative stress are contributing factors to neurodegeneration in physiological aging as well as in age-related neurological disorders. Neuroinflammation can be both a cause and a result of chronic oxidative stress. The role of the oxidative stress and free radicals in the development of Alzheimer's disease (AD) is currently the focus of many studies. Hydrogen peroxide (H2O2) in AD is...

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PMID: 23202440
DOI: 10.3233/JAD-120940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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