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Article

Coumarin derivatives protection against ROS production in cellular models of Abeta toxicities.

Free radical research - 1 Oct 2007

Kontogiorgis Christos A, Xu Yanan, Hadjipavlou-Litina Dimitra, Luo Yuan

Abstract excerpt

The role of oxidative stress and free radicals in the development of Alzheimer's disease (AD) has been the focus of many recent studies. The role of hydrogen peroxide (H(2)O(2)) in AD is thought to be associated with Abeta (amyloid - beta) damage in cells. A number of coumarin derivatives were previously found to be potent anti-inflammatory and antioxidant agents. Herein, these coumarin derivatives were tested as...

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Identifiers

PMID: 17886039
DOI: 10.1080/10715760701447884

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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