Article
Brain-derived neurotrophic factor Val66Met polymorphism is not associated with primary dystonia in a Chinese population.
Neuroscience letters - 15 Jan 2013
Ma Lingyan, Chen Yi, Wang Lin, Yang Yingmai, Cheng Fubo, Tian Yuan, Wan Xinhua
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) is a modulator of synaptic and neural plasticity. Considering the association between dystonia and abnormal sensorimotor cortex plasticity, BDNF may be a candidate gene that confers susceptibility to dystonia. However, the association between Val66Met polymorphism of BDNF gene and primary dystonia is controversial. METHODS: A case-control study was performed to...
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