Article
Val66Met polymorphism of brain-derived neurotrophic factor is associated with idiopathic dystonia.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Mar 2015
Sako Wataru, Murakami Nagahisa, Izumi Yuishin, Kaji Ryuji
Abstract excerpt
The Val66Met (G196A; rs6265) single nucleotide polymorphism of brain-derived neurotrophic factor (BDNF) affects morphology and neuronal activity, and is expected to be associated with central nervous system disorders. However, it remains controversial whether Val66Met polymorphism is a risk factor for idiopathic dystonia. We aimed to clarify the impact of BDNF polymorphism on idiopathic dystonia. A literature...
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