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Article

Locating a lipid at the portal to the lipoxygenase active site.

Biophysical journal - 21 Nov 2012

Gaffney Betty J, Bradshaw Miles D, Frausto Stephen D, Wu Fayi, Freed Jack H, Borbat Peter

Abstract excerpt

Lipoxygenase enzymes initiate diverse signaling pathways by specifically directing oxygen to different carbons of arachidonate and other polyunsaturated acyl chains, but structural origins of this specificity have remained unclear. We therefore determined the nature of the lipoxygenase interactio...

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Identifiers

PMID: 23200047
DOI: 10.1016/j.bpj.2012.10.002
PMCID: PMC3512035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23200047-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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