Article
Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection.
1 May 1991
Abstract excerpt
During latent Epstein-Barr virus (EBV) infection of human B lymphocytes, six viral nuclear antigen (EBNAs) are expressed from long primary transcripts by means of alternative splicing and alternative polyadenylylation sites. These transcripts initiate from one of two promoters, Cp or Wp, that function in a mutually exclusive fashion. Wp is exclusively utilized during the initial stages of infection of primary B...
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