Article
The rs8506 TT Genotype in lincRNA-NR_024015 Contributes to the Risk of Sepsis in a Southern Chinese Child Population.
Frontiers in public health - 1 Jan 2022
Li Jinqing, Zhou Huazhong, Wei Bing, Che Di, Xu Yufen, Pi Lei, Fu Lanyan, Hong Jie, Gu Xiaoqiong
Abstract excerpt
Background: Sepsis is a highly life-threatening heterogeneous syndrome and a global health burden. Studies have shown that many genetic variants could influence the risk of sepsis. Long non-coding RNA lincRNA-NR_024015 may participate in functional alteration of endothelial cell via vascular endothelial growth factor (VEGF) signaling, whereas its relevance between the lincRNA-NR_024015 polymorphism and sepsis...
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