Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional Repression of E-Cadherin by Human Papillomavirus Type 16 E6

26 Nov 2012

Abstract excerpt

There is increasing evidence supporting DNA virus regulation of the cell adhesion and tumour suppressor protein, E-cadherin. We previously reported that loss of E-cadherin in human papillomavirus (HPV) type 16-infected epidermis is contributed to by the major viral proto-oncogene E6 and is associated with reduced Langerhans cells density, potentially regulating the immune response. The focus of this study is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cervical Cancer and HPV Research
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23189137
DOI: 10.1371/journal.pone.0048954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional Repression of E-Cadherin by Human Papillomavirus Type 16 E6PMID 23189137Read ↗

Epigenetic repression of E-cadherin by human papillomavirus 16 E7 proteinSemantic proximity Read ↗

Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytesSemantic proximity Read ↗

Modulation of DNA methylation by human papillomavirus E6 and E7 oncoproteins in cervical cancer (Review)Semantic proximity Read ↗

Human papillomavirus 16 E6 and E7 synergistically repress innate immune gene transcriptionSemantic proximity Read ↗

Deregulation of E-cadherin by human papillomavirus is not confined to high-risk, cancer-causing typesSemantic proximity Read ↗

The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoterSemantic proximity Read ↗

Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene TranscriptionSemantic proximity Read ↗

Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogrammingSemantic proximity Read ↗

Evidence for Alteration of EZH2, BMI1, and KDM6A and Epigenetic Reprogramming in Human Papillomavirus Type 16 E6/E7-Expressing KeratinocytesSemantic proximity Read ↗

The Differentiation-Specific Factor CDP/Cut Represses Transcription and Replication of Human Papillomaviruses through a Conserved Silencing ElementSemantic proximity Read ↗

Enhanced oncogenicity of Asian-American human papillomavirus 16 is associated with impaired E2 repression of E6/E7 oncogene transcriptionSemantic proximity Read ↗

High-Risk Human Papillomavirus E7 Alters Host DNA Methylome and Represses HLA-E Expression in Human KeratinocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.