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Article

A novel drug candidate for Alzheimer's disease treatment: gx-50 derived from Zanthoxylum bungeanum.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Tang Maoping, Wang Zhaoxia, Zhou Ying, Xu Wangjie, Li Shengtian, Wang Lianyun, Wei Dongqing, Qiao Zhongdong

Abstract excerpt

This study focused on a promising drug candidate, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-acrylamide (gx-50), a compound extracted from Sichuan pepper (Zanthoxylum Bungeanum), to determine whether it would be an effective therapeutic for Alzheimer's disease (AD) via biological experiments. In vivo, we determined the pharmacokinetic profile of gx-50 and evaluated the effect of gx-50 on the cognitive abilities of...

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Identifiers

PMID: 23186988
DOI: 10.3233/JAD-121831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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