Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Depichering the Effects of Astragaloside IV on AD-Like Phenotypes: A Systematic and Experimental Investigation.

Oxidative medicine and cellular longevity - 1 Jan 2021

Wang Xuncui, Gao Feng, Xu Wen, Cao Yin, Wang Jinghui, Zhu Guoqi

Abstract excerpt

Astragaloside IV (AS-IV) is an active component in Astragalus membranaceus with the potential to treat neurodegenerative diseases, especially Alzheimer's diseases (ADs). However, its mechanisms are still not known. Herein, we aimed to explore the systematic pharmacological mechanism of AS-IV for treating AD. Drug prediction, network pharmacology, and functional bioinformatics analyses were conducted. Molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drugs, Chinese Herbal
Share to Molecular Docking Simulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuroinflammatory Diseases

Share to Phytotherapy

Share to PPAR gamma

Share to Saponins

Share to Support Vector Machine

Share to Triterpenes

Source

Open in PubMed Open full text

Identifiers

PMID: 34616501
DOI: 10.1155/2021/1020614
PMCID: PMC8487832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Depichering the Effects of Astragaloside IV on AD-Like Phenotypes: A Systematic and Experimental Investigation.PMID 34616501Read ↗

Exploring the potential mechanism of Polygonatum sibiricum for Alzheimer's disease based on network pharmacology and molecular dockingSemantic proximity Read ↗

Network Pharmacology and molecular docking approach to unveil the mechanism of <i>Hypericum perforatum</i> in the management of Alzheimer’s disorderSemantic proximity Read ↗

The Network Pharmacology Study And Molecular Docking To Investigate The Potential Mechanism of Acoritataninowii Rhizoma Against Alzheimer's DiseaseSemantic proximity Read ↗

Exploring the therapeutic potential of natural compounds for Alzheimer's disease: Mechanisms of action and pharmacological propertiesSemantic proximity Read ↗

Mechanisms of action of formononetin, an extract from Astragalus membranaceus medicinal plant, in ameliorating Alzheimer’s diseaseSemantic proximity Read ↗

Uncovering Active Ingredients and Mechanisms of Pholiota adiposa in the Treatment of Alzheimer's disease: A Study Based on Network Pharmacology and BioinformaticsSemantic proximity Read ↗

Network Pharmacology-guided Identification and Molecular Validation of Multi-Target Phytoconstituents from Gmelina arborea against Alzheimer’s DiseaseSemantic proximity Read ↗

Network Pharmacology-guided Identification and Molecular Validation of Multi-Target Phytoconstituents from Gmelina arborea against Alzheimer’s DiseaseSemantic proximity Read ↗

Polyphenols in the Pipeline: Network-Based Docking, Molecular Dynamics and ADMET Studies of Flavonoids against Alzheimer’s diseaseSemantic proximity Read ↗

Molecular Mechanism of Huanglian Jiedu Decoction in Treatment of Alzheimer’s Disease based on Network PharmacologySemantic proximity Read ↗

Screening of active ingredients in Kaixin Powder for Alzheimer’s disease based on molecular dockingSemantic proximity Read ↗

Targeting PD-1/PD-L1-MAPK1 Signaling by a Novel Synergistic Combination of Rivastigmine and Epigallocatechin in Alzheimer’s Disease: An Integrated Insilico ApproachSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.