Article
Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.
PloS one - 1 Jan 2012
György Bence, Szabó Tamás G, Turiák Lilla, Wright Matthew, Herczeg Petra, Lédeczi Zsigmond, Kittel Agnes, Polgár Anna, Tóth Kálmán, Dérfalvi Beáta, Zelenák Gergő, Böröcz István, Carr Bob, Nagy György, Vékey Károly, Gay Steffen, Falus András, Buzás Edit I
Abstract excerpt
INTRODUCTION: Microvesicles (MVs), earlier referred to as microparticles, represent a major type of extracellular vesicles currently considered as novel biomarkers in various clinical settings such as autoimmune disorders. However, the analysis of MVs in body fluids has not been fully standardized yet, and there are numerous pitfalls that hinder the correct assessment of these structures. METHODS: In this study,...
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