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Article

Chicken-or-egg question: Which came first, extracellular vesicles or autoimmune diseases?

28 Feb 2020

Abstract excerpt

Extracellular vesicles (EVs) have attracted great interest as contributors to autoimmune disease (AD) pathogenesis, owing to their immunomodulatory potential; they may also play a role in triggering tolerance disruption, by delivering auto-antigens. EVs are released by almost all cell types, and afford paracrine or distal cell communication, functioning as biological carriers of active molecules including lipids,...

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PMID: 32108378
DOI: 10.1002/jlb.3mr0120-232r

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