Article
The optimal mutagen dosage to induce point-mutations in Synechocystis sp. PCC6803 and its application to promote temperature tolerance.
PloS one - 1 Jan 2012
Tillich Ulrich M, Lehmann Sandra, Schulze Katja, Dühring Ulf, Frohme Marcus
Abstract excerpt
Random mutagenesis is a useful tool to genetically modify organisms for various purposes, such as adaptation to cultivation conditions, the induction of tolerances, or increased yield of valuable substances. This is especially attractive for systems where it is not obvious which genes require modifications. Random mutagenesis has been extensively used to modify crop plants, but even with the renewed interest in...
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