Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered expression of carbonic anhydrase-related protein XI in neuronal cells expressing mutant ataxin-3.

Cerebellum (London, England) - 1 Jun 2013

Hsieh Mingli, Chang Wei-Hsiu, Hsu Chi-Fu, Nishimori Isao, Kuo Cheng-Liang, Minakuchi Tomoko

Abstract excerpt

Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is a late-onset neurodegenerative disorder caused by the expansion of a polyglutamine tract within the gene product, ataxin-3. Microarray analysis revealed a dramatic differential expression of carbonic anhydrase-related protein XI (CA-RPXI/CA11) in the presence or absence of mutant ataxin-3. Therefore, we examined the expression and distribution of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxin-3
Share to Green Fluorescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Machado-Joseph Disease

Share to Nerve Tissue Proteins

Share to Neuroblastoma

Share to Nuclear Proteins

Share to Oligonucleotide Array Sequence Analysis

Share to Repressor Proteins

Source

Identifiers

PMID: 23184527
DOI: 10.1007/s12311-012-0430-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered expression of carbonic anhydrase-related protein XI in neuronal cells expressing mutant ataxin-3.PMID 23184527Read ↗

An Isoform of Ataxin‐3 Accumulates in the Nucleus of Neuronal Cells in Affected Brain Regions of SCA3 PatientsSemantic proximity Read ↗

Blood and cerebellar abundance of <i>ATXN3</i> splice variants in spinocerebellar ataxia type 3/Machado-Joseph diseaseSemantic proximity Read ↗

Machado‐Joseph disease gene product is a cytoplasmic protein widely expressed in brainSemantic proximity Read ↗

T1-11 and JMF1907 ameliorate polyglutamine-expanded ataxin-3-induced neurodegeneration, transcriptional dysregulation and ataxic symptom in the SCA3 transgenic mouseSemantic proximity Read ↗

A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats.Semantic proximity Read ↗

Expression and Functional Study of Single Mutations of Carbonic Anhydrase 8 in Neuronal Cells.Semantic proximity Read ↗

Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence.Semantic proximity Read ↗

Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models.Semantic proximity Read ↗

Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasionSemantic proximity Read ↗

Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3.Semantic proximity Read ↗

Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.Semantic proximity Read ↗

Carbonic anhydrase related protein VIII and its role in neurodegeneration and cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.