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Article

Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3.

Journal of neuropathology and experimental neurology - 1 Oct 2003

Evert Bernd O, Vogt Ina R, Vieira-Saecker Ana M, Ozimek Lucia, de Vos Rob A I, Brunt Ewout R P, Klockgether Thomas, Wüllner Ullrich

Abstract excerpt

Spinocerebellar ataxia type 3 (SCA3) is a late-onset neurodegenerative disorder caused by the expansion of a polyglutamine tract within the gene product, ataxin-3. We have previously shown that mutant ataxin-3 causes upregulation of inflammatory genes in transgenic SCA3 cell lines and human SCA3...

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PMID: 14575237
DOI: 10.1093/jnen/62.10.1006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14575237-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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