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Article

Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models.

The Journal of cell biology - 15 Feb 2016

Matos Carlos A, Nóbrega Clévio, Louros Susana R, Almeida Bruno, Ferreiro Elisabete, Valero Jorge, Pereira de Almeida Luís, Macedo-Ribeiro Sandra, Carvalho Ana Luísa

Abstract excerpt

Different neurodegenerative diseases are caused by aberrant elongation of repeated glutamine sequences normally found in particular human proteins. Although the proteins involved are ubiquitously distributed in human tissues, toxicity targets only defined neuronal populations. Changes caused by an expanded polyglutamine protein are possibly influenced by endogenous cellular mechanisms, which may be harnessed to...

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Identifiers

PMID: 26880203
DOI: 10.1083/jcb.201506025
PMCID: PMC4754714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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