Article
Association of Arg194Trp, Arg280His and Arg399Gln polymorphisms in X-ray repair cross-complementing group 1 gene and risk of differentiated thyroid carcinoma in Iran.
Iranian biomedical journal - 1 Jan 2011
Fard-Esfahani Pezhman, Fard-Esfahani Armaghan, Fayaz Shima, Ghanbarzadeh Bahareh, Saidi Parinaz, Mohabati Reyhaneh, Bidoki Seyed Kazem, Majdi Mina
Abstract excerpt
BACKGROUND: X-ray repair cross-complementing group 1 (XRCC1) gene is a DNA repair gene and its non-synonymous single nucleotide polymorphisms (SNP) may influence DNA repair capacity which has been considered as a modifying risk factor for cancer development. METHODS: A case-control study was conducted to investigate impact of three frequently studied polymorphisms (Arg194Trp, Arg280His and Arg399Gln) on...
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